MIXED NICKEL (II) COMPLEXES OF SCHIFF BASE AND DITHIOCARBAMATES: SYNTHESES, SPECTROSCOPIC STUDIES AND ANTI-BACTERIAL INVESTIGATION

Oloyede, H.O.* Famobuwa, O.E; Fehintola, E.O; Omodara, N.B; Oyebade, A;

Akinwale, M.A. and Adegoke, O.T

Department of Chemistry, Adeyemi College of Education, P.M.B, 520, Ondo, Nigeria

* Corresponding author: Tel.: +2348064998701

E-mail address: langmuir_isottherm@yahoo.com; hammedoloyede150@yahoo.com

 

Abstract

The syntheses, physico-chemical characterization and antibacterial activity studies of some nickel(II) complexes ofdialkyldithiocarbamates (dtc) mixed with a Schiff base, Methylphenylsalicylaldiminate (MePhSal) are reported in this artile. These dithiocarbamate ligands are diethyl (Et2), dibenzyl (Bz2), di-isobutyl (i-Bu2), di-n-butyl (n-Bu2), Methylbutyl (MeBu), Ethylbutyl (EtBu) Methylphenyl (MePh) and cyclohexyl (c-HxMe). The result of the elemental analyses correspond to 1:1:1 stoichiometry of the nickel(II) ion to the ligands. Infrared spectra studies show bidentatecoordination of the Schiff base to the nickel atom through the azomethine nitrogen and phenolic oxygen while the dithiocarbamate ligands chelated through both sulphur donor-atoms.  The solid reflectance spectra and magnetic moment data of the complexes show d-d absorption bands typical of four coordinate, tetrahedral/square planar geometry. The complexes were tested against strains of some bacteria viz: Staphylococcus aureus and Bacillus subtilis (Gram positive); Escherichia coli, Pseudomonas aeruginosa and Salmonella typhi (Gram negative). The complexes found inactive against all the test bacteria. This may be due to the poor solubility of the complexes in the solvent.

Keywords: nickel(II) complexes, syntheses, spectroscopic, dithiocarbamates, Schiff base, antibacterial activity